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When oral administration of medication is not possible, an alternative method needs to be considered to ensure that the medication is still effectively delivered into the animal's system. Subcutaneous injection is a viable option because it allows the medication to be injected into the layer of fat and tissue underneath the skin. This method is particularly useful for medications that can be absorbed slowly and steadily, providing a prolonged effect.

Subcutaneous injections have several advantages. They are relatively simple to administer, require minimal training, and are less invasive compared to other injection routes. Additionally, this method provides a way to administer fluids, vaccines, or medications in situations where an animal may be vomiting, unconscious, or otherwise unable to take medication orally.

Other methods of administration, such as rectal administration, inhalation, and intramuscular injection, may be appropriate in certain contexts, but they either require specific circumstances or may not be preferable compared to the subtleness and ease of subcutaneous injections in general veterinary practice. Therefore, considering the ease of administration and effectiveness, subcutaneous injection stands out as the best alternative when oral routes are compromised.